Methotrexate - CaLiGraph

Property	Value
rdf:type	Hepatotoxin World Health Organization essential medicine Mammalian dihydrofolate reductase inhibitor owl:NamedIndividual Compounds with carbon number 20 Disease-modifying antirheumatic drug Immunosuppressant MeSH code (D03) Orphan drug Drug: Met Drug known for off-label use Antileukemic drug IARC Group 3 carcinogen Benzamide Folate Antineoplastic agent Chemotherapeutic agent Antifolate Nephrotoxin
rdfs:label	Methotrexate
owl:sameAs	dbr:Methotrexate
prov:wasDerivedFrom	http://en.wikipedia.org/wiki/Category:Nephrotoxins http://en.wikipedia.org/wiki/Immunosuppressive_drug http://en.wikipedia.org/wiki/Management_of_Crohn's_disease http://en.wikipedia.org/wiki/Indirect_abortion http://en.wikipedia.org/wiki/Lymphoma http://en.wikipedia.org/wiki/Category:Hepatotoxins http://en.wikipedia.org/wiki/Intrathecal_administration http://en.wikipedia.org/wiki/Hydroxychloroquine http://en.wikipedia.org/wiki/Burkitt_lymphoma http://en.wikipedia.org/wiki/List_of_antileukemic_drugs http://en.wikipedia.org/wiki/Scleroderma http://en.wikipedia.org/wiki/Category:Orphan_drugs http://en.wikipedia.org/wiki/List_of_MeSH_codes_(D03) http://en.wikipedia.org/wiki/List_of_drugs:_Fm%E2%80%93Ft http://en.wikipedia.org/wiki/List_of_drugs:_Tr%E2%80%93Tri http://en.wikipedia.org/wiki/Histiocytosis http://en.wikipedia.org/wiki/List_of_antineoplastic_agents http://en.wikipedia.org/wiki/List_of_chemotherapeutic_agents http://en.wikipedia.org/wiki/Hypersegmented_neutrophil http://en.wikipedia.org/wiki/Category:Mammalian_dihydrofolate_reductase_inhibitors http://en.wikipedia.org/wiki/Psoriatic_onychodystrophy http://en.wikipedia.org/wiki/Category:World_Health_Organization_essential_medicines http://en.wikipedia.org/wiki/IARC_group_3 http://en.wikipedia.org/wiki/Solute_carrier_organic_anion_transporter_family_member_1B3 http://en.wikipedia.org/wiki/WHO_Model_List_of_Essential_Medicines http://en.wikipedia.org/wiki/WHO_Model_List_of_Essential_Medicines_for_Children http://en.wikipedia.org/wiki/Biological_half-life http://en.wikipedia.org/wiki/Fenoprofen http://en.wikipedia.org/wiki/Granada_medium http://en.wikipedia.org/wiki/List_of_drugs_known_for_off-label_use http://en.wikipedia.org/wiki/Side_effect http://en.wikipedia.org/wiki/Graft-versus-host_disease http://en.wikipedia.org/wiki/Sequential_high-dose_chemotherapy http://en.wikipedia.org/wiki/Category:Disease-modifying_antirheumatic_drugs http://en.wikipedia.org/wiki/Category:Immunosuppressants http://en.wikipedia.org/wiki/Disease-modifying_antirheumatic_drug http://en.wikipedia.org/wiki/List_of_compounds_with_carbon_number_20 http://en.wikipedia.org/wiki/Folate_deficiency http://en.wikipedia.org/wiki/Antifolate http://en.wikipedia.org/wiki/Dicloxacillin http://en.wikipedia.org/wiki/Rheumatoid_nodule http://en.wikipedia.org/wiki/List_of_drugs:_Met http://en.wikipedia.org/wiki/Neuromyelitis_optica_spectrum_disorder http://en.wikipedia.org/wiki/Antimetabolite http://en.wikipedia.org/wiki/Management_of_ulcerative_colitis http://en.wikipedia.org/wiki/Drug-induced_aseptic_meningitis http://en.wikipedia.org/wiki/Cutaneous_T_cell_lymphoma http://en.wikipedia.org/wiki/Hyper-CVAD http://en.wikipedia.org/wiki/Metamizole http://en.wikipedia.org/wiki/IMEP_(chemotherapy) http://en.wikipedia.org/wiki/Triple_therapy http://en.wikipedia.org/wiki/Breast_milk http://en.wikipedia.org/wiki/Cerebral_vasculitis http://en.wikipedia.org/wiki/Developmental_toxicity http://en.wikipedia.org/wiki/Category:Folates http://en.wikipedia.org/wiki/Miscarriage http://en.wikipedia.org/wiki/Senile_pruritus http://en.wikipedia.org/wiki/Anemia http://en.wikipedia.org/wiki/Category:IARC_Group_3_carcinogens http://en.wikipedia.org/wiki/Hepatotoxin http://en.wikipedia.org/wiki/Thrombocytopenia http://en.wikipedia.org/wiki/Table_of_volume_of_distribution_for_drugs http://en.wikipedia.org/wiki/Chemotherapy-induced_nausea_and_vomiting http://en.wikipedia.org/wiki/Category:Antifolates http://en.wikipedia.org/wiki/Category:Benzamides http://en.wikipedia.org/wiki/Teva_Pharmaceuticals
skos:prefLabel	Methotrexate
skos:altLabel	Folex '''(M)'''ethotrexate Trexall amethopterin methotrexate methotrexate toxicity
clgo:alternativeName	Trexall, Rheumatrex, Otrexup, others
clgo:bioavailability	60.0
clgo:casNumber	59-05-2
clgo:chEBI	44185
clgo:chEMBL	34259
clgo:drugbank	DB00563
clgo:fdaUniiCode	YL5FZ2Y5U1
clgo:kegg	D00142
clgo:medlinePlus	a682019
clgo:pubchem	126941
is clgo:knownFor of	Yellapragada Subbarow
is clgo:medication of	Dermatomyositis Lupus Crohn's disease Scleroderma
is clgo:treatment of	Ectopic pregnancy

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